Results 101 to 110 of about 1,981,488 (283)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Classification of Obfuscation Techniques in LLVM IR: Machine Learning on Vector Representations

open access: yesMachine Learning and Knowledge Extraction
We present a novel methodology for classifying code obfuscation techniques in LLVM IR program embeddings. We apply isolated and layered code obfuscations to C source code using the Tigress obfuscator, compile them to LLVM IR, and convert each IR code ...
Sebastian Raubitzek   +3 more
doaj   +1 more source

Software code protection through software obfuscation [PDF]

open access: yes, 2019
The mode of platform-independent software running on client machine has various advantages. But it also introduces some problems, such as how to guard against software piracy, how to protect user from intellectual property theft and from attacks by malicious modifications.
openaire   +2 more sources

Sequential Innovation, Patents, and Imitation [PDF]

open access: yes
We argue that when discoveries are "sequential" (so that each successive invention builds in an essential way on its predecessors) patent protection is not as useful for encouraging innovation as in a static setting.
Eric Maskin, James Bessen
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

The pirate from Koenigsberg: why closed source software is not worth of copyright protection [PDF]

open access: yes
According to Kant, property applies only to touchable things, among which he includes the works of art. For the very principle of private property, a legitimate purchaser has the right to replicate and to share them without restrictions.
Pievatolo, Maria Chiara
core   +1 more source

Windows Software Protection Against Reverse Engineering [PDF]

open access: yes, 2011
Tato práce se zabývá seznámením se se zpětným inženýrstvím, způsoby jeho použití a zneužití v praxi a seznámením se s existujícími nástroji na ochranu softwaru a s nástroji projektu Lissom.
Korvas, Pavol
core  

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Consensus-Based Load Frequency Control of a Multi-Area Power System

open access: yesIEEE Access
The integration of renewable energy sources into modern power grids presents challenges for load frequency control (LFC) due to the increased system dynamics and uncertainties introduced by variable generation sources. Traditional LFC methods are limited
Ravi Patel   +3 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

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