Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Software services protection security protocol based on software watermarking in cloud environment
Aimed to resist the infringement of software services in cloud environment,a software services protection security protocol based on software watermarking in cloud environment was presented.On the consideration of actual needs in cloud computing,the ...
Jin-chao XU, Guo-sun ZENG, Wei WANG
doaj +2 more sources
Network Externality and Commercial Software Piracy [PDF]
Contrary to the earlier findings under end-users piracy where the existence of strong network externality was shown to be a reason for allowing limited piracy, we find when the piracy is commercial in nature the optimal policy for the original software ...
Sougata Poddar
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Proteção de software por certificação digital [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Computação.Este trabalho é uma proposta para um combate mais eficaz contra cópias não autorizadas de programas de computador.
Rocha, João Luiz Francalacci
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
The Software Invention Cube: A classification scheme for software inventions [PDF]
The patent system protects inventions. The requirement that a software invention should make ‘a technical contribution’ turns out to be untenable in practice and this raises the question, what constitutes an invention in the realm of software.
Bergstra, J.A. +6 more
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Network Externality and Software Piracy [PDF]
copyright, software piracy, network externality, market structure ...
Poddar, Sougata
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A dinâmica dos mecanismos de proteção e compartilhamento de conhecimento, no processo de desenvolvimento de software, em um empresa pública de tecnologia da informação (TI) [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia e Gestão do Conhecimento, Florianópolis, 2014.O objetivo desta tese é descrever a dinâmica de funcionamento dos mecanismos de proteção ...
Carvalho, Isamir Machado de
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