Results 131 to 140 of about 11,455,886 (297)
Software people and software quality: a qualitative exploratory research on how workforce management can enhance the product quality in software companies. [PDF]
, 2011 The aim of this work is to investigate how to address the management of individuals in a software company to positively affect the quality of the software product.
Sortino, Elena
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY, 2012 In the given paper I present the information regarding quality metrics. Different quality factors can be imposing with relation to cost, schedule and rework. It’s very important to make quality assurance plans. For that you have to cover many milestones which can be represented in time sheets.
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Scientists' needs in modelling software ecosystems [PDF]
, 2015 Currently the landscape of software ecosystem modelling methods and languages is like Babel after the fall of the tower: There are many methods and languages available and interchanging data between researchers and organizations that actively govern ...
Jansen, Slinger +6 more
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
A systematic literature review of open source software quality assessment models. [PDF]
Springerplus, 2016 Adewumi A +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
A survey of Canadian medical physicists: software quality assurance of in-house software. [PDF]
J Appl Clin Med Phys, 2015 Salomons GJ, Kelly D.
europepmc +1 more source