Results 191 to 200 of about 11,494,549 (358)

Eighth International Workshop on Requirements Engineering—Foundation for Software Quality (REFSQ'02) [PDF]

, 2003
Camille Salinesi, Björn Regnell
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Repeatability of gray value-based bone density measurements in cone beam computed tomography (CBCT) images under different acquisition protocols. [PDF]

BMC Oral Health
Martins LAC, Szalewski L, Pałka K, Kalinowski P, Cavalcanti MGP, Różyło-Kalinowska I.   +5 more
europepmc   +1 more source

Culture shock: Improving software quality

, 1988
Kor de Jong, Sharon L. Trauth
openalex   +1 more source

Software quality lessons from medical device failure data

, 1999
Dolores R Wallace, D. Richard Kuhn
openalex   +1 more source

A quality-model-based approach for describing and evaluating software packages [PDF]

, 2003
Xavier Franch, Juan Pablo Carvallo
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Whole-genome sequencing and variants data of 304 indigenous goats from Southwest China. [PDF]

Sci Data
Zhang J, Zhou D, Yang R, Guo Z, Tian X, Zhao Y.   +5 more
europepmc   +1 more source

MCNP{trademark} Software Quality Assurance plan

, 1996
H.M. Abhold, J.S. Hendricks
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source