Results 221 to 230 of about 11,494,549 (358)

Cell-free DNA as a potential alternative to genomic DNA in genetic studies. [PDF]

NAR Genom Bioinform
Zeng J, Zhu H, Wang Y, Zeng G, Liu P, Ou R, Lan X, Zheng Y, Zhao C, Li L, Zhang H, Yin J, Liao M, Zhang Y, Jin X.   +14 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Generating reliable software project task flows using large language models through prompt engineering and robust evaluation. [PDF]

Sci Rep
Sarim M, Masood F, Maheshwari M, Faridi AR, Shamsan AH.   +4 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

An open letter to the NIH: value and costs in publishing. [PDF]

J Clin Invest
Jackson S, Guth KD, Hawley JB, Williams CL, Hsue PY, Eickelberg O, McNally EM.   +6 more
europepmc   +1 more source

Assessing Software Quality Through Visualised Cohesion Metrics

, 2001
Timothy K. Shih, Ming-Chi Lee, Teh-Sheng Huang, Lawrence Y. Deng   +3 more
openalex   +2 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Chloroplast genome characteristics and phylogenetic analysis of <i>Mangifera indica</i> L. 'Guiqi' and <i>M. quadrifida</i> Jack (anacardiaceae). [PDF]

Mitochondrial DNA B Resour
Meng K, Qin Y, Qu J, Lee SY, Lu L, Zou P, Huang G.   +6 more
europepmc   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Impact of Guided Implant Dentistry on Patient Quality of Life, Satisfaction, and Psychological Well-Being: A Systematic Review. [PDF]

J Clin Med
García-Valdez D, Velasco-Ortega E, Ortiz-Garcia I, Monsalve-Guil L, López-López J, Núñez-Márquez E, Matos-Garrido N, Jiménez-Guerra Á, Moreno-Muñoz J, Rondón-Romero JL.   +9 more
europepmc   +1 more source