Results 61 to 70 of about 416,738 (278)
There have been discussed key points of operational activates in a large scale geographically spread software development projects. A look taken at required QA processes structure in such project.
Святослав Аркадійович МУРАВЕЦЬКИЙ +1 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Recent decades have witnessed transformative advances in radiation physics and computer technology, revolutionizing the precision of radiation therapy.
Mayank Dhoundiyal +5 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Purpose: The process of housing delivery all over the world is confronted by multiple barriers resulting in houses that are short of clients’ expectations in terms of quality and overall standards.
Mbazor David N. +2 more
doaj +1 more source
Telecommunications Network Planning and Maintenance [PDF]
Telecommunications network operators are on a constant challenge to provide new services which require ubiquitous broadband access. In an attempt to do so, they are faced with many problems such as the network coverage or providing the guaranteed Quality
Alarcón Mondéjar, Martín Javier +3 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
This study explores engineering-oriented quality assurance (QA) practices within software localization, emphasizing the evaluation of graphical user interface (GUI) elements translated via Google Machine Translation (MT).
Sina Alizadeh Tabrizi
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

