Results 41 to 50 of about 14,811,766 (247)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Software Reliability Prediction Based on Recurrent Neural Network and Ensemble Method
ComputersSoftware reliability is a crucial factor in determining software quality quantitatively. It is also used to estimate the software testing duration. In software reliability testing, traditional parametric software reliability growth models (SRGMs) are ...
Wafa Alshehri +2 more
doaj +1 more source
Using Amsaa Model in Evaluating Reliability Growth Testing [PDF]
المجلة العراقية للعلوم الاحصائية, 2019 Reliability growth is defined as the positive progress in reliability over a period of time according to changes in product design or manufacturing processes. There are three main areas of reliability growth: planning, tracking and projecting.
Karam Nageeb, Khalida Ahmed
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
IEEE Access, 2019 This paper proposes a generalized model to cover imperfect debugging and the uncertainty of the operating environment and its effect on fault detection rate into software reliability evaluation based on a non-homogeneous Poisson process (NHPP). Many NHPP
Qiuying Li, Hoang Pham
doaj +1 more source
Mathematics, 2021 This paper presents a general testing coverage software reliability modeling framework that covers imperfect debugging and considers not only fault detection processes (FDP) but also fault correction processes (FCP).
Qiuying Li, Hoang Pham
doaj +1 more source
Software Reliability Model with Dependent Failures and SPRT
Mathematics, 2020 Software reliability and quality are crucial in several fields. Related studies have focused on software reliability growth models (SRGMs). Herein, we propose a new SRGM that assumes interdependent software failures.
Da Hye Lee, In Hong Chang, Hoang Pham
doaj +1 more source
Queueing-Based Simulation for Software Reliability Analysis
IEEE Access, 2022 As modern software system is growing in size and complexity, the customer expectations for software quality have become higher. In the past, many software reliability growth models (SRGMs) were proposed and they are helped to evaluate the quality of ...
Jhih-Sin Lin, Chin-Yu Huang
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source