Results 71 to 80 of about 473,501 (260)

MLBRSA: Multi-Learning-Based Reptile Search Algorithm for Global Optimization and Software Requirement Prioritization Problems. [PDF]

Biomimetics (Basel), 2023
Kailasam JK, Nalliah R, Nallagoundanpalayam Muthusamy S, Manoharan P.   +3 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Element quality indicator: A quality assessment and defect detection method for software requirement specification. [PDF]

Heliyon, 2023
Zhi Q, Gong L, Ren J, Liu M, Zhou Z, Yamamoto S.   +5 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

APPLYING FUNCTION POINT METHOD TO MEASURE ENTREPRENEURSHIP SYSTEM SIZE AT UiTM

Malaysian Journal of Computing
Traditional estimation methods for assessing the size and scope of software systems often result in inaccuracies, leading to budget overruns and timeline delays.
Gazairi Ghazali, Mohd Hairy Mohamaddiah, Ahmad Sobri Abdul Haris, Syarifah Nurul Afzan Syed Mohammed   +3 more
doaj   +1 more source

Ensemble Balanced Nested Dichotomy Fuzzy Models for Software Requirement Risk Prediction

IEEE Access
Modern software systems are becoming more intricate, making identification of risks in the software requirement phase— a fundamental aspect of the software development life cycle (SDLC)—complex.
Ganesh Kumar, Abdullahi Abubakar Imam, Shuib Basri, Ahmad Sobri Hashim, Abdul Ghani Haji Naim, Luiz Fernando Capretz, Abdullateef Oluwagbemiga Balogun, Hussaini Mamman   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Software Requirement Smells and Detection Techniques: A Systematic Literature Review

Cybernetics and Information Technologies
One of the major reasons for software project failure is poor requirements, so numerous requirement smells detection solutions are proposed. Critical appraisal of the proposed requirement fault detection methods is crucial for refining knowledge of ...
Alemneh Esubalew, Berhanu Fekerte
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source