Results 101 to 110 of about 8,678,122 (349)

New Deep Learning-Based Approach for Source Code Generation: Application to Computer Vision Systems

open access: yesAI
Deep learning has enabled significant progress in source code generation, aiming to reduce the manual, error-prone, and time-consuming aspects of software development.
Wafa Alshehri   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Software requirements: Guidance and control software development specification [PDF]

open access: yes
The software requirements for an implementation of Guidance and Control Software (GCS) are specified. The purpose of the GCS is to provide guidance and engine control to a planetary landing vehicle during its terminal descent onto a planetary surface and
Buckland, R. C.   +3 more
core   +1 more source

A Conceptual UX-aware Model of Requirements

open access: yes, 2016
User eXperience (UX) is becoming increasingly important for success of software products. Yet, many companies still face various challenges in their work with UX.
Feldt, Robert   +3 more
core   +2 more sources

Aligning Healthcare Innovation and Software Requirements through Design Thinking

open access: yes2016 IEEE/ACM International Workshop on Software Engineering in Healthcare Systems (SEHS), 2016
In recent years, there has been significant growth in software companies across the healthcare sector developing new technologies to improve healthcare delivery and services.
N. Carroll, Ita Richardson
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A Systematic Approach to Diagnostic Laboratory Software Requirements Analysis. [PDF]

open access: yesBioengineering (Basel), 2022
Krause T   +4 more
europepmc   +1 more source

A Model for Quality Optimization in Software Design Processes [PDF]

open access: yes, 2005
The main objective of software engineers is to design and implement systems that implement all functional and non-functional requirements. Unfortunately, it is very difficult or even generally impossible to deliver a software system that satisfies all ...
Aksit, Mehmet   +2 more
core   +1 more source

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