Results 191 to 200 of about 719,114 (264)

Development and validation of an artificial intelligence proof-of-concept tool for risk-based quality assessment of generic medicines: a South African case study. [PDF]

Front Med (Lausanne)
Danks L, Semete-Makokotlela B, Reynecke C, Dijeng S, Kgosietsile B, van Tonder J, van Graan C, Hinch J, Kruger A, Walker S, Salek S.   +10 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Biomedical open source software: Crucial packages and hidden heroes. [PDF]

PLoS Comput Biol
Brown EM, Druskat S, Hébert-Dufresne L, Howison J, Mietchen D, Nesbitt A, Pimentel JF, Veytsman B.   +7 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

A framework for reproducibly managing coupled research software and data assets based on shared transformation functions. [PDF]

Patterns (N Y)
Kuckertz P, Fuchs B, Schönau J, Gardian H, Knosala K, Arellano Ruiz ES, Göpfert J, Gils HC, Weinand JM, Jochem P, Linßen J, Stolten D.   +11 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Development of reconfigurable smart medical wards using integrated components and complex features. [PDF]

Front Digit Health
Veerapaneni RK, Delhibabu R, Levonevskiy D, Zhukova N.   +3 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

CnQuant: high-resolution chromosomal copy number profiling for precision oncology in the clinics. [PDF]

Acta Neuropathol
Freyter BM, Hultschig C, Brugger J, Bratic Hench I, Frank S, Hench J.   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source