Results 51 to 60 of about 142,756 (307)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Havacılık ve Uzay Teknolojileri Dergisi, 2022 A multidisciplinary rotor blade design approach, which is suitable for conceptual design, sizing and evaluation of helicopters is presented. Blade outer surface and structural geometry is represented by a geometrical model in which chord, thickness ratio,
Hasan İBAÇOĞLU, Aytaç ARIKOĞLU
doaj
Development of raised access floor panel by optimisation techniques [PDF]
, 2015 Raised access floor panels currently have a chipboard core and are encapsulated within thin layer of galvanised steel. Two key problems with these raised access floor panels are that they are heavy because of the chipboard and expensive, as the cost of ...
Cheah, HC
core
The Project Scheduling Problem with Non-Deterministic Activities Duration: A Literature Review [PDF]
, 2018 Purpose: The goal of this article is to provide an extensive literature review of the models and solution procedures proposed by many researchers interested on the Project Scheduling Problem with nondeterministic activities duration.
Diaz-Serna, F. Javier +1 more
core +4 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Design of Grid-Connected Solar PV Power Plant in Riyadh Using PVsyst
EnergiesSolar energy is a quick-producing source of energy in Saudi Arabia. Solar photovoltaic (PV) energy accounts for 0.5% of electricity output, with a total installed capacity of 9.425 GW and 9353 solar power plants of various types globally.
Mubarak M. Alkahtani +3 more
doaj +1 more source
Energies, 2018 To increase the electrical power quality, in the last decades, an intense development in the last decades of high-performance equipment built as advanced power electronics applications, such as the compensators from Switching Power Converter category ...
Adrian Pană +2 more
doaj +1 more source
Energy Production Analysis and Optimization of Mini-Grid in Remote Areas: The Case Study of Habaswein, Kenya [PDF]
, 2017 Rural electrification in remote areas of developing countries has several challenges which hinder energy access to the population. For instance, the extension of the national grid to provide electricity in these areas is largely not viable.
DEL CITTO, Riccardo +8 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source