Results 91 to 100 of about 117,876 (267)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Part of PP103 Minisymposterium: Software Productivity and Sustainability for CSE and Data Science2019 SIAM Conference on Computational Science and EngineeringSustaining Student SoftwareA university research group focused on CSE software development can generate an enormous amount of software very quickly. Not all of it can (or should) be sustained.
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The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
Defining Software Sustainability
While at WSSSPE4 discussing possible WSSSPE mission statements, the question of what software sustainability is has been raised.
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ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
The growing concern over the state of degradation of the environment has led to a consideration of aspects relating to sustainability in software. Bearing this in mind, we have carried out a survey of practitioners, aiming to gather information about ...
José Alberto García-Berna +5 more
doaj +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Sustainability and social responsibility reporting in open source software
Digital commons have held the interest of the research community in recent years. However, institutional recognition has not been fully awarded mainly due to the absence of a comprehensive reporting framework. The objective of our research is to identify
Maria Isabel Alonso de Magdaleno +1 more
doaj +1 more source
WOSSS: Software Engineering for Software Sustainability
Slides presented at WOSSS 19, Den Haag, The Netherlands. Study reference: Mário Rosado de Souza, Robert Haines, Markel Vigo, Caroline Jay; What Makes Research Software Sustainable? An Interview Study With Research Software Engineers.; accepted at 12th International Workshop on Cooperative and Human Aspects of Software Engineering (CHASE) @ ICSE 2019;
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