Results 81 to 90 of about 6,415,956 (313)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Potential impacts for monitoring sustainability: case study of hollow fiber membrane [PDF]
, 2017 Sustainability level is a new indicator of quality and efficiency for product life cycle. Sustainability should be balanced among Triple Bottom Line (TBL) aspects namely environmental, economic and social elements.
Hemdi, Abdul Rahman +3 more
core
A Comparison of Software Quality Characteristics and Software Sustainability Characteristics
International Symposium on Computer Science and Intelligent Control, 2019 Software sustainability has generated much interest in the software engineering field in recent times, and has been widely investigated across different fields and from different standpoints.
Sulaiman Aljarallah, R. Lock
semanticscholar +1 more source
, 2020 (PSIP) —a lightweight, iterative workflow where teams identify their most urgent software bottlenecks and work to overcome them. We explain how teams are more productively tackling science goals through PSIP advances in areas such as software builds ...
M. Heroux +31 more
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Sustainability design in requirements engineering: state of practice [PDF]
, 2016 Sustainability is now a major concern in society, but there is little understanding of how it is perceived by software engineering professionals and how sustainability design can become an embedded part of software engineering process.
Becker, Christoph +6 more
core +1 more source
Software Sustainability & High Energy Physics
, 2020 A report from the "Sustainable Software in HEP" IRIS-HEP blueprint workshop: https://indico.cern.ch/event/930127/
Katz, Daniel S. +18 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Fourth Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE4)
Journal of Open Research Software, 2018 This article summarizes motivations, organization, and activities of the Fourth Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE4).
Daniel S. Katz +15 more
doaj +1 more source
Introducing the FAIR Principles for research software
Scientific Data, 2022 Research software is a fundamental and vital part of research, yet significant challenges to discoverability, productivity, quality, reproducibility, and sustainability exist.
Michelle Barker +10 more
doaj +1 more source