Results 161 to 170 of about 31,509,895 (367)

A novel approach to analyzing the evolution of SARS-CoV-2 based on visualization and clustering of large genetic data compactly represented in operative memory

open access: yesВавиловский журнал генетики и селекции
SARS-CoV-2 is a virus for which an outstanding number of genome variants were collected, sequenced and stored from sources all around the world. Raw data in FASTA format include 16.8 million genomes, each ≈29,900 nt (nu­cleotides), with a total size of ...
A. Yu. Palyanov, N. V. Palyanova
doaj   +1 more source

Investigating the Usability, Efficacy and Accuracy of a Medication Entering Software System for a Healthcare Robot. [PDF]

open access: yesFront Robot AI, 2022
Martini N   +7 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Flight test of a resident backup software system [PDF]

open access: yes
A new fault-tolerant system software concept employing the primary digital computers as host for the backup software portion has been implemented and flight tested in the F-8 digital fly-by-wire airplane.
Deets, D. A., Lock, W. P., Megna, V. A.
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

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