Results 211 to 220 of about 8,038,703 (314)
Software Engineering Challenges For Mutable Agent Systems
, 2004 Ladislau Bölöni +4 more
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Evaluating the Implementation of the EndoTool Glycemic Control Software System. [PDF]
Diabetes Spectr, 2018 John SM, Waters KL, Jivani K.
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
BioPARR: A software system for estimating the rupture potential index for abdominal aortic aneurysms. [PDF]
Sci Rep, 2017 Joldes GR +5 more
europepmc +1 more source
Making the case for reforming the I/O software stack of extreme-scale systems
, 2016 Florin Isailă +4 more
openalex +2 more sources
A Module-System Discipline for Model-Driven Software Development [PDF]
, 2017 Sebastian Erdweg, Klaus Ostermann
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Data for the elaboration of the CIPROS checklist with items for a patient registry software system: Examples and explanations. [PDF]
Data Brief, 2017 Lindoerfer D, Mansmann U.
europepmc +1 more source