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We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
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IEEE Transactions on Automatic Control, 1993
A short historical perspective is given of the evolution of the use of software for the realization of increasingly complex control systems. The state-of-the-art in designing computer-based control systems is discussed and highlighted with an example. Two major aspects of the difficulties encountered with the current approach to designing these systems
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A short historical perspective is given of the evolution of the use of software for the realization of increasingly complex control systems. The state-of-the-art in designing computer-based control systems is discussed and highlighted with an example. Two major aspects of the difficulties encountered with the current approach to designing these systems
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IEEE Software, 2013
Systems software is the low-level infrastructure that applications run on. As an applications programmer, first try to find existing systems software rather than writing it from scratch. Once you start writing systems software, use the most efficient algorithms and data structures that gracefully accommodate the workload.
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Systems software is the low-level infrastructure that applications run on. As an applications programmer, first try to find existing systems software rather than writing it from scratch. Once you start writing systems software, use the most efficient algorithms and data structures that gracefully accommodate the workload.
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Systems Software and Applications Software
1985When driving a car we are making use of it. A set of driving skills is needed if we are to make use of the car. These skills, or sets of routines, are learned over a period of time. They would involve such things as knowing how much to turn the steering wheel when going around a corner, how to synchronise the pedal movements when changing gear, how to ...
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Compliance check software system
Proceedings of the 16th International Conference on Computer Systems and Technologies, 2015In this paper a set of functions for a compliance check language implemented in a limit software system is described. It is intended generally for the financial industry but it can also be used for any other field requiring similar automatic observation of limits on the allowed operations.
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