Results 161 to 170 of about 3,405,045 (356)

DNN Robustness Enhancement Based on Adversarial Sample Prioritization

IEEE Access
Adversarial attacks pose significant threats to the robustness of deep neural networks (DNN), necessitating the development of effective defense mechanisms.
Long Zhang, Jiangzhao Wu, Siyuan Ma, Jian Liu   +3 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Implementation and testing of optimization software

, 1978
Jorge J. Morè
openalex   +2 more sources

Using modern software tools to design, simulate and test a Level 1 trigger sub-system for the D Zero detector [PDF]

, 1996
R. Angstadt, F. Borcherding, M. Johnson, Leonardo Marmo Moreira   +3 more
openalex   +1 more source

The Role of Artificial Intelligence and Machine Learning in Software Testing [PDF]

arXiv
Artificial Intelligence (AI) and Machine Learning (ML) have significantly impacted various industries, including software development. Software testing, a crucial part of the software development lifecycle (SDLC), ensures the quality and reliability of software products.
arxiv  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Savannah River Plant Californium-252 Shuffler software manual. [ASSAY; TEST]

, 1979
S.S. Johnson, T.W. Crane, G.W. Eccleston
openalex   +2 more sources

A proposed software test service for special functions [PDF]

, 1997
Daniel W. Lozier
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Quality programming: Developing and testing software with statistical quality control

, 1988
Barbara Kitchenham
openalex   +1 more source