Results 191 to 200 of about 701,784 (261)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Limited discriminant validity of health belief and 3C models in high HPV vaccine coverage settings: the moderating role of <i>hukou</i> and structural barriers. [PDF]

Front Public Health
Liu Y, Zhao K, Sun W, Jiang N, Li Y, Wang M, Sun Y, Zhang Y, Gao Y, Cao W.   +9 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Fit one model, report one number: how to analyse a training or intervention study. [PDF]

Front Physiol
Schappacher-Tilp G, Tilp M.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

When Artificial Intelligence Agrees Too Easily: The Emerging Risk of Artificial Intelligence Sycophancy in Dentistry. [PDF]

Int Dent J
Turky M, Dummer PMH.
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Protocol for fluorescent false neurotransmitter live imaging of dopamine release dynamics from individual synapses in acute brain slices. [PDF]

STAR Protoc
Cottilli P, Mosharov EV, Devine MJ, Sulzer DL.   +3 more
europepmc   +1 more source

Setting expectations for current and future directions of native mass spectrometry in the biopharmaceutical industry. [PDF]

MAbs
Hecht E, Martin E, Liko I, Mahan A, Sahasrabuddhe A, Tajoddin NN, Campuzano IDG.   +6 more
europepmc   +1 more source

Clinical decision support tool evaluation: Correction of direct oral anticoagulant dosing errors by clinical pharmacists and physicians. [PDF]

Res Pract Thromb Haemost
Saraswat A, Smith SN, Dorsch MP, Fabbri M, Seagull J, Choi SY, Lanham M, Barnes GD.   +7 more
europepmc   +1 more source