Results 71 to 80 of about 684,761 (260)

Not Real or too Soft? On the Challenges of Publishing Interdisciplinary Software Engineering Research

open access: yes2025 IEEE/ACM 47th International Conference on Software Engineering: Software Engineering in Society (ICSE-SEIS)
The discipline of software engineering (SE) combines social and technological dimensions. It is an interdisciplinary research field. However, interdisciplinary research submitted to software engineering venues may not receive the same level of recognition as more traditional or technical topics such as software testing.
Sonja M. Hyrynsalmi   +3 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

AUTOMATED SYSTEM FOR MEASURINGTHE PARAMETERS OF DIFFRACTION ON POLYMER FILMS WITH PERIODIC MICRORELIEF

open access: yesRUDN Journal of Engineering Research, 2015
An automated system for measuring the diffraction efficiency of light, as well its kinematic scheme, were designed and assembled. The measurements of the diffraction efficiency of light on the sample of polymeric substrates with periodic microrelief were
V V Belyaev   +9 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A multi-layered software architecture model for building software solutions in an urbanized information system

open access: yesInternational Journal of Information Systems and Project Management, 2022
The concept of Information Systems urbanization has been proposed since the late 1990’s in order to help organizations building agile information systems. Nevertheless, despite the advantages of this concept, it remains too descriptive and presents many
Sana Bent Aboulkacem Guetat   +1 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

NeoCoMM: Neocortical neuro-inspired computational model for realistic microscale simulations

open access: yesSoftwareX
The ability to simulate a neocortical neural network activity at the cellular level is of great interest in many studies. It allows for the investigation of microscopic mechanisms in both healthy and pathological brains.
Mariam Al Harrach   +2 more
doaj   +1 more source

A multi-layered software architecture model for building software solutions in an urbanized information system

open access: yesInternational Journal of Information Systems and Project Management, 2013
The concept of Information Systems urbanization has been proposed since the late 1990’s in order to help organizations building agile information systems.
Sana Guetat, Salem Dakhli, , ,
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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