Results 171 to 180 of about 3,928,828 (299)

BaPreS: a software tool for predicting bacteriocins using an optimal set of features. [PDF]

BMC Bioinformatics, 2023
Akhter S, Miller JH.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

mzQuality: An Open-Source Software Tool for Quality Monitoring and Reporting of Targeted Mass Spectrometry Measurements. [PDF]

J Am Soc Mass Spectrom
van der Peet M, Maas P, Wegrzyn A, Lamont L, Fleming R, Bordes C, Debette S, Harms A, Hankemeier T, Kindt A.   +9 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A software tool for applying Bayes' theorem in medical diagnostics. [PDF]

BMC Med Inform Decis Mak
Chatzimichail T, Hatjimihail AT.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

A deep learning software tool for automated sleep staging in rats via single channel EEG. [PDF]

NPP Digit Psychiatry Neurosci
Smith A, Milosavljevic S, Wright CJ, Grant CA, Pocivavsek A, Valafar H.   +5 more
europepmc   +1 more source

Microkinetic engine (μKE): a software tool for (micro)kinetic modeling [PDF]

, 2012
Kumar, Vinod, Marin, Guy, Thybaut, Joris
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

IDAC-BioDose, a complete biokinetic and dosimetric software tool designed for diagnostic nuclear medicine and built on the ICRP computational framework. [PDF]

Radiat Prot Dosimetry
Andersson M, Leggett R, Eckerman K, Mattsson S.   +3 more
europepmc   +1 more source