Results 161 to 170 of about 23,466 (213)

Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites. [PDF]

Nat Commun
Delgado-Tejedor A, Medina R, Begik O, Cozzuto L, López J, Blanco S, Ponomarenko J, Novoa EM.   +7 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

[Letter to the editor of the article "Artificial intelligence in primary care: Friend or foe?"] [PDF]

Aten Primaria
Garcia Narda A.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Application of 3-dimensional reconstruction via modified pulmonary artery computed tomography angiography in anatomic pulmonary segmentectomy. [PDF]

J Cardiothorac Surg
Min W, Zhang J, Zhu Y, Jin L.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Draft genome sequences of '<i>Candidatus</i> Liberibacter solanacearum' haplotype E isolated from carrot psyllids in France. [PDF]

Microbiol Resour Announc
Remenant B, Cousseau-Suhard P, Leroux A, Blanchard Y, Loiseau M.   +4 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Income-Based analysis of health security in Western Asia through an integrated GHSI, MCDM, and Clustering Model. [PDF]

F1000Res
Nasser AA, Alghawli ASA, Saleh S, Elsayed AAK.   +3 more
europepmc   +1 more source