Results 91 to 100 of about 153,413 (338)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Experimental study on soil-water characteristic curve of expensive soil considering net normal stress

Yantu gongcheng xuebao, 2018
The expansive soil is a kind of special soil with swell-shrinking, fractured and over-consolidated properties. In engineering construction, the expansive soil is generally under unsaturated state and complex applied stress environment. It is practical to
WANG Xiao-qi 1, WANG Shi-ji 1, CHENG Ming-shu 1, LI Xian 1, 2, ZHOU Chao-yun 1, HE Bing-hui 2
doaj   +1 more source

Comparative Analysis of Soil-Water Characteristic Curve in Fractal and Empirical Models

Advances in Materials Science and Engineering, 2020
The fitting analysis of soil-water characteristic curve (SWCC) is the foundation of engineering properties of unsaturated soils. The purpose of this paper is to explore the differences of fitting effects between different fractal and empirical models as ...
Gaoliang Tao, Yangyang Chen, Henglin Xiao, Yin Chen, Wan Peng   +4 more
doaj   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Evaluating dual porosity of pelletized diatomaceous earth using bimodal soil-water characteristic curve functions

, 2001
Soil-water characteristic curve data for specimens containing either ~1 mm or ~2 mm diameter pellets of processed diatomaceous earth are measured using a variety of methods (Tempe cell, pressure plate, filter paper, and chilled-mirror psychrometer). The
Craig A Burger, Charles D Shackelford
core   +1 more source

Prediction of the Soil–Water Retention Curve of Loess Using the Pore Data from the Mercury Intrusion Technique

, 2023
The soil–water characteristic curve (SWCC) is a crucial input parameter for describing the distribution of soil moisture and water movement in various environmental and geotechnical challenges. It is widely recognized that the SWCC is controlled by
Xiaokun Hou
core   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Experimental Study on Soil Water Characteristic Curve of Compacted Unsaturated Soil

, 2010
Soil water characteristic curve is one of important topics of unsaturated soils. Pressure plate extractor and GDS unsaturated triaxial apparatus are used to study influencing factors including types of soils and net mean stress.
Dong Lin Wang
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

The influence of suction changes on the stiffness of railway formation

, 2011
Despite compacted soils being unsaturated, geotechnical design is predominantly based on saturated soils,despite it being known that differences exist between the behaviour of saturated and unsaturated soils.Suction in soils has been shown to increase ...
Otter, Louise
core