Results 71 to 80 of about 1,858,770 (239)

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

open access: yesAdvanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou   +11 more
wiley   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

open access: yesAdvanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu   +7 more
wiley   +1 more source

Soil Particle Size Distribution Protocol [PDF]

open access: yes, 2003
The purpose of this resource is to sure the distribution of different sizes of soil particles in each horizon of a soil profile. Using dry, sieved soil from a horizon, students mix the soil with water and a dispersing solution to completely separate the ...
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core  

Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu   +8 more
wiley   +1 more source

Modeling soil water availability for neotropical forest trees [PDF]

open access: yes, 2010
The aim of this study was to model the soil water availability to neotropical trees. We developed a discrete-time deterministic water balance model and validated it on a large field data set.
Bonal, Damien   +3 more
core  

Multi‐Factor Optimization of Nickel Foam Flow Fields: Insights into Structural and Surface Modifications for High‐Performance PEMFCs

open access: yesAdvanced Science, EarlyView.
This article investigates the multi‐factor optimization of nickel foam flow fields in PEMFCs, focusing on compression, porosity, pore size, hydrophobicity, and surface coatings. Through comprehensive experiments and analysis, it reveals how structural and surface modifications influence electrochemical performance, water management, and corrosion ...
Siyuan Wu   +5 more
wiley   +1 more source

Upcycling Waste Low‐Density Polyethylene into Highly Crystalline Graphite

open access: yesAdvanced Science, EarlyView.
This study achieved high‐crystallinity graphite from low‐density polyethylene (LDPE) and LDPE products, offering 89.4% carbon yield. Enhanced conductivity and crystallinity support applications in electronics, 3D printing, and photothermal devices.
Woojae Jeong   +8 more
wiley   +1 more source

Mechanically reclaiming abandoned saline soils: a numerical evaluation [PDF]

open access: yes
Water quality / Groundwater / Simulation models / Calibrations / Water table / Water balance / Hydraulics / Soil reclamation / Soil water / Flow / Soil properties / Salinity / Pakistan / Punjab ...
Prathapar, S. A., Qureshi, A. S.
core  

High‐Throughput Fluorescence Screening Enables Globally Consistent Identification of ABA Signaling Modulators

open access: yesAdvanced Science, EarlyView.
This paper establishes a global high‐throughput fluorescence screening (GhitFluors) platform to efficiently identify ABA signaling modulators. It effectively identifies diopyridin, a regulator with strong binding affinity to PYR1, and more than 80% inhibitory activity against HAB1, which is equivalent to ABA.
Yang‐Yang Gao   +13 more
wiley   +1 more source

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