LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
Evaluating associations of oxylipin metabolites and fatty acids with incident and prevalent type 2 diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). [PDF]
Downie CG +24 more
europepmc +1 more source
We established a broadly tunable network‐polymer platform for polyimide‐based precursor membranes, extendable to various diamines. Ultrahigh selectivity with demonstrated aging resistance, and scalability via hollow fiber CMS engineering collectively establishes broad and lasting impact for the membrane science and engineering communities.
Yuhe Cao +6 more
wiley +1 more source
Spatial Metabolomics and Single-Cell Virtual Knockout Screening Reveal Solanesol Improves Parkinson's Disease-like Pathology Based on Lipid Inflammation Mechanism. [PDF]
Li Q +6 more
europepmc +1 more source
Mixing method directly governs interface engineering and electrode morphology during the dry coating of all‐solid‐state battery cathodes. While high‐shear batch mixing yields poor electrode quality and lacks core–shell‐like features, continuous extruder mixing enables strong binder fibrillation and a core–shell‐like coating between the active material ...
Michael Wolf +7 more
wiley +1 more source
Ankle-angle-dependent shear wave velocity of the Achilles tendon and triceps surae during passive dorsiflexion in runners with Achilles tendinopathy. [PDF]
Kunita Y +9 more
europepmc +1 more source
A surface‐informed active learning framework integrated with density functional theory enables resource efficient screening of the NiCoFe ternary composition space. Experimental validation identifies Ni55Co10Fe35 as the optimal composition, exhibiting favorable oxygen evolution reaction kinetics.
Hayun Jeon +5 more
wiley +1 more source
The Effects of Ambient Air Pollutants on Changes in Cardiac Structure and Function. [PDF]
Leiser CL +10 more
europepmc +1 more source
ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source
From prediction to performance: <i>In silico</i>-supported formulation of amorphous solid dispersions for PROTAC NX-2127. [PDF]
Stakemeier A +7 more
europepmc +1 more source

