Results 171 to 180 of about 62,363 (313)

Branched‐Chain Amino Acids and Di‐Alanine Supplementation Attenuates Muscle Atrophy in a Murine Model of Cancer Cachexia

open access: yesActa Physiologica, Volume 241, Issue 7, July 2025.
ABSTRACT Aim Cancer cachexia is a severe metabolic disorder leading to skeletal muscle atrophy. Muscle wasting is a major clinical problem in cachectic patients, as it limits the efficacy of chemotherapeutic treatments and worsens quality of life. Nutritional support based on branched‐chain amino acids (BCAA) has been shown to be a promising approach ...
Mayra Colardo   +7 more
wiley   +1 more source

Investigating A Dose Response Relationship between High Fat Diet Consumption and the Contractile Performance of Isolated Mouse Soleus, EDL and Diaphragm Muscles [PDF]

open access: yes, 2019
A Abdelmoula   +56 more
core   +1 more source

Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes [PDF]

open access: green, 1993
Thomas Paul Arnold   +8 more
openalex   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, Volume 15, Issue 6, Page 940-948, June 2025.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

Mitochondrial Sensitivity to Submaximal [ADP] Following Bed Rest: A Novel Two‐Phase Approach Associated With Fibre Types

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background We recently demonstrated that following a 10‐day exposure to inactivity/simulated microgravity impairments of oxidative metabolism were located ‘upstream’ of mitochondrial function, as evaluated by maximal ADP‐stimulated mitochondrial respiration (JO2max) determined ex vivo.
Lucrezia Zuccarelli   +14 more
wiley   +1 more source

Constitutive assembly of Ca2+ entry units in soleus muscle from calsequestrin knockout mice. [PDF]

open access: yesJ Gen Physiol, 2022
Michelucci A   +5 more
europepmc   +1 more source

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