Results 181 to 190 of about 1,530,017 (399)

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina   +7 more
wiley   +1 more source

Skeletal Muscle PGC-1β Signaling is Sufficient to Drive an Endurance Exercise Phenotype and to Counteract Components of Detraining in Mice [PDF]

open access: yes, 2017
Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and -1β serve as master transcriptional regulators of muscle mitochondrial functional capacity and are capable of enhancing muscle endurance when overexpressed in mice.
Ayala, Julio   +8 more
core   +1 more source

The stretch–shortening cycle effect is not associated with cortical or spinal excitability modulations

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Active muscle stretch before shortening increases force, work and power output compared with shortening only, which is known as the stretch–shortening cycle (SSC) effect. We explored whether neural modulations triggered by active muscle stretch persist during the SSC shortening phase, thereby potentially contributing to the SSC ...
Lea‐Fedia Rissmann   +4 more
wiley   +1 more source

Brief ambulatory reloading elevates muscle protein synthesis but does not prevent disuse atrophy in hindlimb-unloaded rats

open access: yesBiochemistry and Biophysics Reports
Disuse muscle atrophy remains a major challenge in contexts such as prolonged bed rest or microgravity. Here, we investigated whether brief bouts of ambulatory reloading could attenuate skeletal muscle atrophy caused by five days of hindlimb unloading ...
Michael P. Wiggs   +3 more
doaj  

The Effect of SERCA Activation on Functional Characteristics and Signaling of Rat Soleus Muscle upon 7 Days of Unloading. [PDF]

open access: yesBiomolecules, 2023
Sharlo KA   +7 more
europepmc   +1 more source

Effects of Thyrotoxicosis on Mitochondrial Enzymes of Rat Soleus [PDF]

open access: yes, 1979
Cytochrome oxidase, glycerol-3-phosphate dehydrogenase, and succinate dehydrogenase were measured in mitochondrial fractions obtained from rat soleus muscle of control and 8 week T3 + T4 treated animals.
Courtright, James B., Fitts, Robert H.
core   +1 more source

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