Results 111 to 120 of about 2,028,209 (354)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
High-impedance microwave resonators with two-photon nonlinear effects
Nature CommunicationsNonlinear effects play a central role in photonics as they form the foundation for most of the device functionalities such as amplification and quantum state preparation and detection.
S. Andersson +4 more
doaj +1 more source
Strip-loaded nanophotonic interfaces for resonant coupling and single-photon routing
Frontiers in PhysicsWe report on the design and simulation of strip-loaded nanophotonic interfaces aimed at improving resonant coupling and photon routing efficiency. In our design, the guided mode is confined within a plane by a high-index thin film and is loosely confined
Katharine Snow +2 more
doaj +1 more source
Review for "Solid‐State NMR Study of Polymorphism in Tris(8‐hydroxyquinolinate)aluminium"
, 2021 Thierry Azaı̈s
openalex +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A Framework to Simulate Friction Stir Additive Manufacturing (FSAM) Using the Finite Element Method
MicromachinesDefining an accurate friction model without having the mesh distortion in an optimized computational time has always been a significant challenge for modelling solid-state natural processes. The presented paper proposes an Eulerian frictional-based solid
Bahman Meyghani, Reza Teimouri
doaj +1 more source
Solid State Process for Preparation of Nickel Oxide Nanoparticles: Characterization and Optical Study [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2016 In the present work, we report preparation of NiO nanoparticles with well-defined plate morphology by solid-state reaction of NiCl2∙6H2O and the Schiff base ligand N,N′-bis-(3-methoxysalicylidene)benzene-1,4-diamine), as a novel precursor via solid state
Aliakbar Dehno Khalaji
doaj
Nature Communications, 2017 Single molecule magnets have demonstrated promise for information storage, molecular spintronics and quantum computing, but are limited by their low operational temperatures.
Fupin Liu +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source