Results 51 to 60 of about 630,904 (297)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Electrocaloric Cooling Materials and Systems: A Review and Perspective

Zhileng xuebao, 2021
Electrocaloric cooling technology has advanced with the discovery of the giant electrocaloric effect, employing the entropy change during the poling and de-poling processes to enable operation of the refrigeration cycle.
Li Zichao, Shi Junye, Chen Jiangping, Qian Xiaoshi   +3 more
doaj   +2 more sources

Electrocaloric materials and applications based on multilayer ceramic capacitors

Journal of Materiomics
The increasing demand for effective and environmentally compatible cooling technologies has driven significant interest in the development of solid–state cooling materials. Among these, the electrocaloric (EC) system is considered a promising solid–state
Li-Qian Cheng, Yongke Yan, Zhiping Wang, Zhengyu Li, Xiaotian Li   +4 more
doaj   +1 more source

Effects of a cooling channel on the creep damage and failure probability of planar solid oxide fuel cells

Frontiers in Materials, 2023
A solid oxide fuel cell (SOFC) is an all-solid-state chemical power generation device that converts chemical energy into electrical energy in an efficient and environmentally friendly way in medium- and high-temperature environments. However, the thermal
Yun Luo, Yun Luo, Xuqian Chen, Rongjun Liu, Wenchun Jiang, Wenchun Jiang   +5 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Solid-state Laser Cooling

Since the first proof-of-concept demonstrations of photoluminescence-based optical refrigeration, solid-state laser cooling has developed into a credible competitor to conventional cryogenic technologies. Solid-state laser cooling continues to advance as new materials push cooling limits.
Ding, Yang, Zhang, Shenghao, Albrecht, Alexander R., Feng, Zhaojie, Forberger, Lars, Tanaka, Hiroki, Hehlen, Markus P., Nemova, Galina, Pauzauskie, Peter J., Seletskiy, Denis V., Kuno, Masaru   +10 more
openaire   +2 more sources

Cooling electrons by magnetic-field tuning of Andreev reflection

, 2006
A solid-state cooling principle based on magnetic-field-driven tunable suppression of Andreev reflection in superconductor/two-dimensional electron gas nanostructures is proposed.
A. F. Andreev, Carlo Castellana, Fabio Beltram, Fabio Taddei, Francesco Giazotto, J. P. Pekola, Michele Governale, Rosario Fazio   +7 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Anomalous electrocaloric behaviors in (anti)ferroelectrics: a mini-review

Frontiers in Chemistry
Solid-state cooling, represented by the electrocaloric effect (ECE) in (anti)ferroelectric materials, has emerged as an alternative green refrigeration technology by virtue of its high efficiency and miniaturization and is expected to substitute ...
Feng Li, Feng Li, Chunchang Wang, Lei Shan, Lei Shan   +4 more
doaj   +1 more source