Results 61 to 70 of about 703,218 (296)

Mechanical Properties of Glass Forming Systems

open access: yes, 2007
We address the interesting temperature range of a glass forming system where the mechanical properties are intermediate between those of a liquid and a solid.
D. Deng   +6 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Deep Convolutional Neural Networks Object Detector for Real-Time Waste Identification

open access: yesApplied Sciences, 2020
This paper presents an extensive research carried out for enhancing the performances of convolutional neural network (CNN) object detectors applied to municipal waste identification. In order to obtain an accurate and fast CNN architecture, several types
Daniel Octavian Melinte   +2 more
doaj   +1 more source

Application of granular mechanics to the analysis of solid propellants [PDF]

open access: yes, 1963
In this paper a theoretical method is developed for analyzing the mechanical behavior of granular solid propellant materials. The granular nature of the material is specifically taken into account and, the analysis allows for a media composed of non ...
Zak, Adam R.
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Numerical simulation based on FEM/MLS coupling for solid mechanics [PDF]

open access: yes, 2013
This paper presents the development of Meshless Methods based on the weighted least squares approximation (MLS) [1,3,14] to solve 2D mechanical problems.
Ghozzi, Y., Labergere, C., Villon, P.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Second law of thermodynamics and the failure of rock materials [PDF]

open access: yes, 2001
The relation of nonequilibrium thermodynamics to some failure and fracture theories of rock mechanics is investigated. The basic concepts are given to connect failure to the properties of material equations describing the elastic properties.
Ván, Péter, Vásárhelyi, Balázs
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Surface effects on the persistence length of nanowires and nanotubes

open access: yesTheoretical and Applied Mechanics Letters, 2014
Surface effects on the persistence length of quasi-one-dimensional nanomaterials are investigated by using the theory of surface elasticity and the core–shell model of nanobeams.
Hua Liu   +3 more
doaj   +1 more source

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