Results 71 to 80 of about 1,357,393 (263)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Constitutive Equations for Analyzing Stress Relaxation and Creep of Viscoelastic Materials Based on Standard Linear Solid Model Derived with Finite Loading Rate. [PDF]

Polymers (Basel), 2022
Lin CY, Chen YC, Lin CH, Chang KV.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Homoepitaxial Growth and the Electronic Structure of Degenerately Si Doped β‐Ga2O3 (100) Oriented Thin Films

Advanced Electronic Materials
In this work, homoepitaxial growth and in‐depth study on the electronic structure of Si doped β‐Ga2O3 thin films on (100) oriented Fe doped Ga2O3 substrates are reported.
Ziqi Zhang, Yan Wang, Zhenni Yang, Wenjing Xu, Yan Sun, Yihong Chen, Xiangyu Xu, Ye Yang, Duanyang Chen, Xin Dong, Hao Long, Hongji Qi, Kelvin H. L. Zhang   +12 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

High-precision solid Earth tidal geometry (Geo) model

Big Earth Data
Solid Earth tides reflect the Earth’s elastic response to the tidal forces of the Moon and Sun. Studying these tides reveals Earth’s internal structure, response to ocean loading, and the relationship between tides and earthquakes.
Yunfei Zhang, Shengyi Jiao, Haibo Chen, Jungang Yang, Yongfeng Yang, Xianqing Lv   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Health risk reduction behaviors model for scavengers exposed to solid waste in municipal dump sites in Nakhon Ratchasima Province, Thailand

Risk Management and Healthcare Policy, 2012
Phiman Thirarattanasunthon,1 Wattasit Siriwong,1,2 Mark Robson,2–4 Marija Borjan3 1College of Public Health Sciences, Chulalongkorn University, 2Thai Fogarty ITREOH Center, Chulalongkorn University, Bangkok, Thailand; 3School of ...
Thirarattanasunthon P, Siriwong W, Robson M, Borjan M   +3 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Ador-Solid-Set: A coupled simulation model for commercial solid-set irrigated fields

Agricultural Water Management
The last five decades have seen strong developments in irrigation modeling. In solid-set sprinkler irrigation, models have generally been applied to a few sprinklers in a regular arrangement, making them representative of a sector or a field.
Enrique Playán, Nery Zapata, Borja Latorre, José Cavero, Piluca Paniagua, Eva T. Medina, María Angeles Lorenzo, Javier Burguete   +7 more
doaj   +1 more source