Integrating Spatial Proteogenomics in Cancer Research
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Enhancements on a micromechanical constitutive model of solid propellant
Junyoung Hur +3 more
semanticscholar +1 more source
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
Integrated Experimental-Numerical Analysis of HTPB Propellant Casting Optimization and Droplet Dynamics. [PDF]
Guo Z, Rossi R, Xue Y, Wu Y, Fu X.
europepmc +1 more source
Reconfigurable Acoustofluidic Microvortices for Selective Microcargo Delivery
This work introduces a frequency‐encoded, reconfigurable acoustofluidic system that overcomes the low throughput and poor selectivity of conventional micro‐delivery methods. By exploiting discrete microbubble resonances to program adaptive microvortex modes, the platform enables real‐time switching and selective guidance of microscale payloads through ...
Lei Wang +6 more
wiley +1 more source
Advances in PBT Binder and Its Application in Propellants. [PDF]
Zhang N +9 more
europepmc +1 more source
Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao +14 more
wiley +1 more source
New Features on Mechanical Behavior of Polymeric Materials. [PDF]
Collar EP, García-Martínez JM.
europepmc +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Environmental impact and sustainability of nanocellulose-based nitrated polymers in propellants. [PDF]
Ahmad Aljafree NF +3 more
europepmc +1 more source

