Results 111 to 120 of about 3,231,440 (300)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Advanced ScienceExtracting lithium resources from seawater and brine can promote the development of the new energy materials industry. The electrochemical method is green and efficient. Iron phosphate (FePO4) crystal, with its 1D ion channel, holds significant potential
Xiaoyu Zhao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Formation of non-equilibrium germanium-based solid solutions in al-ge-alloys
Nauka ta progres transportu, 2012 This article is devoted to the investigation of phase composition and microstructure of the higher cooled aluminum-germanium alloys. The formation of non-equilibrium germanium solid solutions is shown.
O.Yu. Bereza, O.V. Bereza
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
THE INFLUENCE MECHANISM OF FERRITE GRAIN SIZE ON STRENGTH STRESS AT THE FATIGUE OF LOW-CARBON STEEL
Nauka ta progres transportu, 2014 Purpose. Explanation of the influence mechanism of ferrite grain size on the fatigue strength of low-carbon steel. Methodology. Material for research is the low-carbon steel with 0.1% of carbon contnent.
I. A. Vakulenko, S. V. Proydak
doaj
, 2019 Citation: 'solid solution' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S05735 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Investigating Electrical and Ferroelectric Properties of Nd Doped BiFeO3-PbTiO3 Solid Solutions [PDF]
Iranian Journal of Materials Science and EngineeringThe effect of different Nd and PT compositions on the electrical and ferroelectric properties of (1-y)Bi1-xNdxFeO3-yPbTiO3 solid solutions, where x = 0.05, 0.10, 0.15, 0.20 and y = 0.1, 0.2, 0.3, and 0.4, was investigated to optimise material performance.
Ram Chhavi Sharma
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