Results 121 to 130 of about 9,251,353 (260)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Solid-Liquid Equilibria Modelling for triacylglycerols exhibiting multiple solid phases [PDF]

, 2009
Important end-use properties of vegetable oils based edible products are strong related to the equilibrium between a solid crystalline network and a liquid phase.
Teles dos Santos, Moises, Carrillo Le Roux, Galo, Gerbaud, Vincent   +2 more
core  

Spitrobot-2 advances time-resolved cryo-trapping crystallography to under 25 ms

Communications Chemistry
We previously introduced the spitrobot, a protein crystal plunging system that enables reaction quenching via cryo-trapping with a time resolution in the millisecond range.
Maria Spiliopoulou, Caitlin E. Hatton, Martin Kollewe, Jan-Philipp Leimkohl, Hendrik Schikora, Friedjof Tellkamp, Pedram Mehrabi, Eike C. Schulz   +7 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Pore suppression and performance improvement mechanisms in wire-arc directed energy deposition of 7075 alloy

Virtual and Physical Prototyping
The pore defects and grain coarsening are the main reasons for performance deterioration in wire-arc directed energy deposition (DED) of ultra-high-strength aluminium alloy.
Yuwen Wang, Dongsheng Wu, Ji Chen, Hisaya Komen, Maoai Chen, Hao Su, Chuansong Wu, Manabu Tanaka   +7 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Impact of selected solvent systems on the pore and solid structure of cellulose aerogels. [PDF]

Cellulose (Lond), 2016
Pircher N, Carbajal L, Schimper C, Bacher M, Rennhofer H, Nedelec JM, Lichtenegger HC, Rosenau T, Liebner F.   +8 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Solid-State Structure of Tp‘PtMe₂H, a Dimethylhydrido Platinum(IV) Complex

, 2016
The solid-state X-ray structure of Tp‘PtMe2H has been determined. This platinum(IV) hydride derivative is stable at room temperature and crystallizes in an orthorhombic cell (space group Pcmn, Z = 4, a = 8.1292(8) Å, b = 13.3862(9) Å, and c = 17.9670(16)
Stacy A. O'Reilly (2996601), Joseph L. Templeton (1234962), Peter S. White (52081)   +2 more
core   +1 more source