Results 1 to 10 of about 7,152 (66)
Antibody and Nanobody Radiolabeling with Copper-64: Solid vs. Liquid Target Approach
Molecules, 2023 Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being proposed as theranostic tools in multiple human diseases. While the production of copper-64 using solid targets has been established for many years, its use is limited due ...
Ivanna Hrynchak +8 more
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A Universal Cassette-Based System for the Dissolution of Solid Targets
Molecules, 2021 Cyclotron-based radionuclides production by using solid targets has become important in the last years due to the growing demand of radiometals, e.g., 68Ga, 89Zr, 43/47Sc, and 52/54Mn.
Gabriele Sciacca +7 more
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A Compact Quick-Release Solid Target System for the TRIUMF TR13 Cyclotron
Instruments, 2019 A new solid target system for the TRIUMF TR13 cyclotron that can accommodate target discs with a 1-2-mm thickness and a 28-mm diameter has been developed. The target system design is based on a modified clamping mechanism of a KF-40 vacuum connector, and
Stefan Zeisler +5 more
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Oncofetal Chondroitin Sulfate: A Putative Therapeutic Target in Adult and Pediatric Solid Tumors
Cells, 2020 Solid tumors remain a major challenge for targeted therapeutic intervention strategies such as antibody-drug conjugates and immunotherapy. At a minimum, clear and actionable solid tumor targets have to comply with the key biological requirement of being ...
Nastaran Khazamipour +6 more
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Design of a high power solid target for 211At [PDF]
EPJ Web of Conferences, 2023 The new SPIRAL2 LINAC at GANIL delivers light beams (p, d, alpha,…) with very large intensities. In order to exploit these beams in an optimal way, high power target stations are requested.
Brunet Guillaume +18 more
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Pharmaceutics, 2022 Designing and implementing various radionuclide production methods guarantees a sustainable supply, which is important for medical use. The use of medical cyclotrons for radiometal production can increase the availability of gallium-68 (68Ga ...
Zarif Ashhar +6 more
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Overview of CSNS tantalum cladded tungsten solid Target-1 and Target-2
Nuclear Engineering and Technology, 2022 A solid tungsten target was used at the China Spallation Neutron Source (CSNS) with 100 kW proton beam power. To improve the lifetime, hot isostatic pressing (HIP) process was selected to bond tantalum cladding with tungsten plates.
Shaohong Wei +11 more
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Macrophages as a Potential Immunotherapeutic Target in Solid Cancers
Vaccines, 2022 The revolution in cancer immunotherapy over the last few decades has resulted in a paradigm shift in the clinical care of cancer. Most of the cancer immunotherapeutic regimens approved so far have relied on modulating the adaptive immune system.
Alok K. Mishra +6 more
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Fused Zinc Target for the Production of Gallium Radioisotopes
Instruments, 2019 Gallium-68 is a popular radioisotope for positron emission tomography. To make gallium-68 more accessible, we developed a new solid target for medical cyclotrons.
Stefan Zeisler +4 more
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Instruments, 2019 A 3D-printed metal solid target using additive manufacturing process is a cost-effective production solution to complex and intricate target design. The initial proof-of-concept prototype solid target holder was 3D-printed in cast alloy, Al⁻7Si ...
Sun Chan, David Cryer, Roger I. Price
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