Results 171 to 180 of about 755,181 (358)

Phase I Study of Pazopanib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumors [PDF]

, 2010
Antoinette R. Tan, Afshin Dowlati, Suzanne F. Jones, Jeffrey R. Infante, Jennifer Nishioka, Fang Lei, Jeffrey P. Hodge, Shelby D. Gainer, Thangam Arumugham, A. Benjamin Suttle, Mohammed M. Dar, Joanne Lager, Howard A. Burris   +12 more
openalex   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

261 Evidence for durable anti-tumor responses by TAC-T cells in preclinical models of solid tumors [PDF]

, 2022
Heather MacGregor, Duane Moogk, Stacey X. Xu, Joanne A. Hammill, Philbert Ip, Ling Wang, Swati Shetty, Kyle MacDonald, Laura Shaver, Sailaja Pirati, Prabha Lal, Christopher W. Helsen, Jonathan L. Bramson, Sadhak Sengupta, Andreas G. Bader   +14 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A Phase I study of 9‐nitrocamptothecin given concurrently with capecitabine in patients with refractory, metastatic solid tumors [PDF]

, 2002
M. Dror Michaelson, David P. Ryan, Charles S. Fuchs, Jeffrey G. Supko, Rocio García‐Carbonero, Joseph P. Eder, Jeffrey W. Clark   +6 more
openalex   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Clinical application and optimization strategies for antibody-drug conjugates in solid tumors. [PDF]

J Int Med Res
Qu J, Zhao X, Zhang L, Cai W, Shen M, Liu X, Wei X, Fei F.   +7 more
europepmc   +1 more source

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors [PDF]

, 2018
Xun Huang, Juan Yan, Min Zhang, Yafang Wang, Yi Chen, Xuhong Fu, Rongrui Wei, Xingling Zheng, Zhiwei Liu, Xiong Zhang, Hong Yang, Bingbing Hao, Yanyan Shen, Yi Su, Xiaoji Cong, Min Huang, Minjia Tan, Jian Ding, Meiyu Geng   +18 more
openalex   +1 more source

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

Advanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni, Ilaria Borghi, Francesca Cadamuro, Sophia Dalfino, Riccardo Campanile, Sofia Nizzolo, Valeria Cassina, Francesca Tallia, Julian R. Jones, Francesco Mantegazza, Sabrina Bertini, Lorenzo Moroni, Francesco Nicotra, Laura Russo   +13 more
wiley   +1 more source