Results 21 to 30 of about 540,096 (367)
, 2023 Benign solid liver tumors are frequently discovered during routine sonographic examinations. As a rule, malignant tumors can be excluded using contrast medium-based sectional imaging; however, unclear cases can represent a diagnostic challenge.
Neumann, U.P. +3 more
core +1 more source
Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
npj Breast Cancer, 2021 Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative breast cancer (BC) with low HER2 expression (i.e., 1+ or 2+ and lack of ERBB2 amplification). However, the clinical and molecular features of HER2-low BC are yet to be
Francesco Schettini +26 more
doaj +1 more source
Tumor–platelet interaction in solid tumors [PDF]
International Journal of Cancer, 2012 AbstractElevated platelet counts in patients diagnosed with malignant tumors were first described more than 100 years ago. Today it is well known that in many types of solid tumors, thrombocytosis at the time of diagnosis is associated with shorter survival.
Daniel, Buergy +3 more
openaire +2 more sources
Feasibility of Photofrin II as a radiosensitizing agent in solid tumors - Preliminary results [PDF]
, 2006 Background: Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II.
Wilkowski, Ralf +7 more
core +1 more source
A molecular map of mesenchymal tumors
, 2005 Background: Bone and soft tissue tumors represent a diverse group of neoplasms thought to derive from cells of the mesenchyme or neural crest. Histological diagnosis is challenging due to the poor or heterogenous differentiation of many tumors, resulting
Flanagan, AM +23 more
core +1 more source
Modelling of Tirapazamine effects on solid tumour morphology [PDF]
, 2011 Bioreductive drugs are in clinical practice to exploit the resistance from tumour microenvironments especially in the hypoxic region of tumour. We pre-sented a tumour treatment model to capture the pharmacology of one of the most prominent bioreductive ...
Kazmi, Nabila +5 more
core +1 more source
Molecular Oncology, 2020 Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a deeper
Lisa Quetel +20 more
doaj +1 more source
Nature Communications, 2023 Plasma ctDNA is a promising method to determine patient outcome in multiple cancer types. Here, the authors use shallow WGS to create machine learning signatures to identify tumor phenotypes and predict therapy response in patients with metastatic breast
Aleix Prat +31 more
doaj +1 more source
FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis
Journal of Translational MedicineBackground Acute pancreatitis (AP) presents a significant clinical challenge with limited therapeutic options. The complex etiology and pathophysiology of AP emphasize the need for innovative treatments.
Amaya Lopez-Pascual +18 more
doaj +1 more source