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Neonatal tumors are different from tumors of the older children and knowledge gained from treating older children can not be extrapolated to neonates. Neonates have immature physiology and their haematopoietic and immune systems are not fully developed and the response to therapy is unpredictable.
Aravindan Chandrasekaran
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Table_1_Therapeutic exercise interventions in pediatric survivors of brain cancer and other solid tumors: A scoping review.pdf [PDF]
BackgroundImproved survival rates for children with solid tumors presents an ongoing challenge of how to maximize quality of survivorship and effectively manage the short- and long-term complications of disease and treatment.
Sandler, Carolina X +14 more
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t(12;15)(p13;q25) ETV6/NTRK3 in solid tumors [PDF]
Review on t(12;15)(p13;q25) in solid tumors, with data on clinics, and the genes ...
Huret, Jean-Loup
core +1 more source
MicroRNAs in Solid Tumors [PDF]
MicroRNAs (miRNAs or miRs) are small, noncoding RNAs (approximately 20-22 nucleotides) that have critical functions in cell proliferation, apoptosis, and differentiation. These evolutionarily conserved RNA sequences are the result of a complex sequence of processing steps, which can regulate the expression of tens, and even hundreds, of genes.
Mary, Dillhoff +2 more
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Chronotherapeutics for Solid Tumors
Circadian rhythms are internal manifestations of the 24-h solar day that allow for synchronization of biological and behavioral processes to the external solar day. This precise regulation of physiology and behavior improves adaptive function and survival.
Claire O. Kisamore +4 more
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Metastasis and Tumor Cell Migration of Solid Tumors [PDF]
The developmental process of local and distant metastases represents the major and defining trait of malignant tumors, whereby tumor cells sustain the capability to migrate from the initial tumor site, seed, and grow at a location other than that of the initial tumor [...]
Jens Hoeppner, Peter Bronsert
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Numerical simulation of solid tumor blood perfusion and drug delivery during the “vascular normalization window” with antiangiogenic therapy [PDF]
This Article is provided by the Brunel Open Access Publishing Fund - Copyright @ 2011 Hindawi PublishingTo investigate the influence of vascular normalization on solid tumor blood perfusion and drug delivery, we used the generated blood vessel network ...
Long, Q +13 more
core +1 more source
Growing evidence suggests a clear role of the host immune system in HER2+ breast cancer. In addition, HER2+ breast cancer is generally considered more immunogenic than hormone receptor-positive (HR+)/HER2-, and specific molecular HER2+ subgroups (e.g ...
Gaia Griguolo +4 more
doaj +1 more source
Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the context of KRAS-mutated lung ...
Irati Macaya +31 more
doaj +1 more source

