Results 111 to 120 of about 7,703,070 (342)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Multi-Solid Varieties and Mh-Transducers

open access: yes, 2007
17 pages, 2 figures, Journal "Algebra and Discrete Mathematics", Number 3 (2007), pp. 113-131, http://adm.lnpu.edu.ua/
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Study on Performance of Infectious Waste Sterilizing Set in Kashan Shahid Beheshti Hospital and Determination of its Optimum Operating Condition [PDF]

open access: yesسلامت و محیط, 2012
Background and Objectives; Autoclaving is one of  the methods which sterilizes infectious solid wastes. Since variety of parameters such as temperature, time, and pressure influence autoclave performance, this study was carried out to evaluate the ...
M Heidari   +3 more
doaj  

Heavy Metals Removal and Recovery from Hazardous Leather Sludge

open access: yesChemical Engineering Transactions, 2019
The tanning industry is one of the oldest industries in the world and is known for the production of a wide variety of toxic waste (aqueous and solid) containing chromium salts and other heavy metals.
Loris Pietrelli   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Advances in Toxins and Narcotics Determination Techniques in China During 2013

open access: yesJournal of Forensic Science and Medicine, 2015
Recently, toxin and narcotics detection techniques have been developed in China. A number of new technologies have been applied. The pretreatment technologies such as solid-phase extraction (SPE) techniques, solid-phase microextraction (SPME) techniques,
Ling Zeng   +3 more
doaj   +1 more source

Holonomy perturbations of the Chern-Simons functional for lens spaces

open access: yes, 2018
We describe a scheme for constructing generating sets for Kronheimer and Mrowka's singular instanton knot homology for the case of knots in lens spaces. The scheme involves Heegaard-splitting a lens space containing a knot into two solid tori.
Boozer, David
core  

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