Results 81 to 90 of about 597,740 (256)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Heavy Metals Removal and Recovery from Hazardous Leather Sludge
Chemical Engineering Transactions, 2019 The tanning industry is one of the oldest industries in the world and is known for the production of a wide variety of toxic waste (aqueous and solid) containing chromium salts and other heavy metals.
Loris Pietrelli +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Multi-Solid Varieties and Mh-Transducers
, 2007 17 pages, 2 figures, Journal "Algebra and Discrete Mathematics", Number 3 (2007), pp. 113-131, http://adm.lnpu.edu.ua/
openaire +3 more sources
Study on Performance of Infectious Waste Sterilizing Set in Kashan Shahid Beheshti Hospital and Determination of its Optimum Operating Condition [PDF]
سلامت و محیط, 2012 Background and Objectives; Autoclaving is one of the methods which sterilizes infectious solid wastes. Since variety of parameters such as temperature, time, and pressure influence autoclave performance, this study was carried out to evaluate the ...
M Heidari +3 more
doaj
Advances in Toxins and Narcotics Determination Techniques in China During 2013
Journal of Forensic Science and Medicine, 2015 Recently, toxin and narcotics detection techniques have been developed in China. A number of new technologies have been applied. The pretreatment technologies such as solid-phase extraction (SPE) techniques, solid-phase microextraction (SPME) techniques,
Ling Zeng +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source