Results 51 to 60 of about 915 (263)

Characterization of ash derived from combustion of paper mill waste sludge: Comparison with municipal solid waste incinerator ash

, 2007
Fly ash derived from incineration of Malaysian paper mill waste sludge (PMWS) was physically and chemically characterized in order to determine its potential toxicity as well as its application as cement replacement material.
Kadir, S.A.S.A., Mahazer, S.Z., Siti Zaharah Mahazer, Sharifah Nawirah, Syed-Ariffin, S.N., Alifah Salwa Abdul-malik, Abdul-Malik, A.S., Zurinawati Zamzuri, Yin, C-Y, Zamzuri, Z., Chun Yang Yin, Sharifah Aishah Syed Abdul Kadir   +11 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Unravel melt pool and bubble dynamics during laser powder bed fusion of polyamides using synchrotron X-ray imaging and process simulation

Virtual and Physical Prototyping
Laser powder bed fusion (LPBF) of Polyamide 12 (PA12) using a near-infra-red (NIR) beam is largely unexplored; therefore, the beam-matter interaction, evolution mechanisms of the melt pool and defects remain unclear. Here, we employed a combination of in
Chu Lun Alex Leung, Jabbar Gardy, Mark Isaacs, Shashidhara Marathe, Michał M. Kłosowski, Junji Shinjo, Chinnapat Panwisawas, Peter D. Lee   +7 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Compressive behaviours of lotus-type porous copper fabricated by Gasar process

, 2012
The lotus-type porous copper with various pore structural parameters was fabricated by a novel solid-gas eutectic solidification process (the Gasar process). The effects of porosity and the Angle between load direction and pores axis (ALP) on compressive
Li, Zaijiu, Li, Zhenhua, Jiang, Yehua, Zhou, Rong, Yang, Tianwu, Jin, Qinglin   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Selective Laser Sintering of a Stainless Steel Powder [PDF]

, 2003
The research presented in this thesis was part of a larger collaborated project (LastForm Programme) to research engineering solutions for the rapid manufacture of large scale (0.5m – 5.0m in length) low, medium and high temperature tooling (from room ...
Hauser, Carl
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Investigations on solidification and fluid flows during GTA welding with in-situ observations

, 2017
International audienceThe relation between fluid flows, solidification mechanisms and welding parameters during GTA weld­ ing of a Cu30Ni plate is investigated.
Soulié, Fabien, Deschaux-Beaume, Frédéric, Chiocca, Alexis, Bordreuil, Cyril   +3 more
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