Results 31 to 40 of about 13,789 (180)

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Solitary Fibrous Tumor [PDF]

, 2020
Solitary fibrous tumor is a neoplasm with an intermediate biological aggressiveness and is classified among fibroblastic-myofibroblastic tumors.
  +5 more sources

Cytologic and Histological Features Distinguishing Myxoid Meningioma From Chordoid Meningioma: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT Meningiomas are the most common primary brain tumors worldwide and are classified into 15 subtypes in the 5th edition of the WHO classification. Myxoid meningioma, characterized by the presence of a mucinous matrix within the tumor, is a rare metaplastic meningioma subtype classified as WHO grade 1.
Tatsuya Aso, Miyuki Yoshino, Manabu Fukuda, Kazuhiko Yuzawa, Mikiko Takahashi   +4 more
wiley   +1 more source

Fourth ventricular solitary fibrous tumor: a case report and review of the literature

Journal of Medical Case Reports, 2012
Introduction Solitary fibrous tumors of the central nervous system usually present as dura-based masses and clinically resemble meningiomas. There are very few reported cases of intra-ventricular solitary fibrous tumors, particularly in the fourth ...
Wang Congli, Manucha Varsha, Faro Scott, Weaver Michael, Mukherjee Abir L   +4 more
doaj   +1 more source

A rare case of solitary fibrous tumor of the liver and highly differentiated rectal adenocarcinoma

Исследования и практика в медицине, 2021
Solitary fibrous tumors (SFT) are rare spindle cell mesenchymal neoplasms of presumably fibroblastic origin with undefined malignancy potential and rare metastasis.
S. A. Shinkarev, M. N. Lando, V. N. Brykin, R. V. Zhinkin, O. E. Pestryakov, D. A. Odegov   +5 more
doaj   +1 more source

Case report: Solitary fibrous tumor of the paracervical uterus combined with vaginal wall adenocarcinoma

Frontiers in Medicine
BackgroundSolitary fibrous tumors are rare mesenchymal tumors that typically occur in the pleura. Solitary fibrous tumors of the uterine cervix are uncommon.
Xiaowei Zhang, Jun Chen, Junqiang Du, Jiajia Ying   +3 more
doaj   +1 more source

Solitary Fibrous Tumor of the Retroperitoneal Space

Case Reports in Surgery, 2021
A solitary fibrous tumor develops from mesenchymal cells as a pleural neoplasm, but it is also occasionally reported in extrapleural sites. Retroperitoneal tumors are a group of neoplasms located between muscles and the fascia of the posterior abdominal ...
Mateusz Marcinek, Konrad Majcherczyk, Marcel Nowak, Aleksander Targoński, Michał Tkocz   +4 more
doaj   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, EarlyView.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

Combination therapy with preoperative embolization and en block laminectomy using thread saw for spinous process solitary fibrous tumor: A case report

Radiology Case Reports, 2020
Solitary fibrous tumors are rare mesenchymal neoplasms with highly recurrence rates after intratumor resection. We report 2 cases of solitary fibrous tumors treated with combination therapy with embolization and en bloc laminectomy using thread saw.
Tomohiro Yamada, MD, Tomohiko Hasegawa, MD, PhD, Yoji Shido, MD, PhD, Yu Yamato, MD, PhD, Go Yoshida, MD, PhD, Tatsuya Yasuda, MD, PhD, Tomohiro Banno, MD, PhD, Hideyuki Arima, MD, PhD, Shin Oe, MD, PhD, Hiroki Ushirozako, MD, PhD, Koichiro Ide, MD, Yuh Wanatabe, MD, Yukihiro Matsuyama, MD, PhD   +12 more
doaj   +1 more source

Ossifying spindled and epithelioid tumour: Expanding the clinical and morphologic spectrum of a recently described entity

Histopathology, EarlyView.
Ossifying spindled and epithelioid tumour (OSET) can show unusual morphologic features, including minimal or absent peripheral ossification, eosinophil‐rich stroma, increased mitotic activity (≥5 mitotic figures per 10 high‐power fields), and necrosis.
Rayan M Sibira, Benjamin F Smith, Amy Davis, Jessica L Davis, Nada Mohamed, Riyam Zreik, David J Papke Jr., Michael Michal, Sintawat Wangsiricharoen, Karen J Fritchie   +9 more
wiley   +1 more source