Results 171 to 180 of about 900,679 (330)

TEXTURA DO SOLO: CONCEITOS E APLICAÇÕES EM SOLOS ARENOSOS

, 2017
Luana Nunes Centeno, M. D. F. Guevara, S. T. Cecconello, R. O. Sousa, Luís Carlos Timm   +4 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Variáveis ambientais e a distribuição de espécies arbóreas em um remanescente de floresta estacional semidecídua montana no campus da Universidade Federal de Lavras, MG

Acta Botânica Brasílica, 2002
Este trabalho teve como objetivo detectar padrões de distribuição espacial da comunidade arbórea de um fragmento de floresta estacional semidecídua montana e suas relações com variáveis ambientais, com ênfase nas variações catenárias do solo e efeito das
Espírito-Santo Fernando Del Bon, Oliveira-Filho Ary Teixeira de, Machado Evandro Luiz Mendonça, Souza Josival Santos, Fontes Marco Aurélio Leite, Marques João José Granate de Sá Melo   +5 more
doaj  

Geopedologia e a sua influência sobre espécies arbóreas em florestas fluviais. [PDF]

, 2014
A recuperação de florestas fluviais compreende uma série de ações, sendo a primeira identificar a unidade fitogeográfica em que se está trabalhando. Na seqüência, a bacia hidrográfica deve ser compartimentada geopedologicamente, buscando identificar suas
CURCIO, G. R., SEVEGNANI, L., UHLMANN, A.   +2 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Adsorção de tebutiurom em áreas de recarga do Aqüífero Guarani . [PDF]

, 2017
O potencial de contaminação de águas subterrâneas por agrotóxicos depende da mobilidade do produto no solo, que pode ser avaliada de diferentes formas.
BOEIRA, R. C., FERRACINI, V. L., GOMES, M. A. F., MAIA, A. de H. N., SOUZA, M. D. de   +4 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Curcuminoids can prevent post-contrast acute kidney injury in chronic kidney disease patients: A randomized controlled trial. [PDF]

Medicine (Baltimore), 2022
Jaturapisanukul S, Kurathong S, Ngamvichchukorn T, Trakarnvanich T.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source