Results 351 to 360 of about 1,983,588 (386)
Some of the next articles are maybe not open access.
Solubility and partitioning I: Solubility of nonelectrolytes in water
Journal of Pharmaceutical Sciences, 1980On the basis of a semiempirical analysis, an equation was obtained that enables the estimation of the aqueous solubility of either liquid or crystalline organic nonelectrolytes: (see formula in text) where log PC and delta Sf are estimated from the chemical structure and MP is either known or experimentally determined.
Shri C. Valvani, Samuel H. Yalkowsky
openaire +3 more sources
Molecular Pharmaceutics, 2015
The supersaturation potential of poorly water-soluble compounds is of interest in the context of solubility enhancing formulations for enhanced bioavailability.
Luis Almeida e Sousa +3 more
semanticscholar +1 more source
The supersaturation potential of poorly water-soluble compounds is of interest in the context of solubility enhancing formulations for enhanced bioavailability.
Luis Almeida e Sousa +3 more
semanticscholar +1 more source
Solubility behavior of an organic soluble polyimide
Journal of Applied Polymer Science, 1990AbstractThe solubility behavior of an organic soluble polyimide synthesized from 3,3′,4,4′‐benzophenone tetracarboxylic dianhydride and 2,3,5,6‐tetramethyl‐p‐phenylene diamine in about 60 liquids was investigated via solubility experiments. These results were put into a computer program to obtain a three‐dimensional representation of the polymer ...
Hurng-Rern Lee, Yu-Der Lee
openaire +2 more sources
Solubility and Partitioning VII: Solubility of Barbiturates in Water
Journal of Pharmaceutical Sciences, 1987The solubility equation of Yalkowsky was used to estimate the aqueous solubility of 33 barbiturates in the temperature range of 5 to 45 degrees C. The equation was extended by adding a term which accounts for the effect of pH on the solubility of the drug.
Rodolfo Pinal, Samuel H. Yalkowsky
openaire +3 more sources
Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals
, 2011The current phase of drug development is witnessing an oncoming crisis due to the combined effects of increasing R&D costs, decreasing number of new drug molecules being launched, several blockbuster drugs falling off the patent cliff, and a high ...
N. Babu, A. Nangia
semanticscholar +1 more source
Solubility of sparingly-soluble electrolytes–a new approach
Analytical Methods, 2010The technique of solid titration was developed to explore the true solution equilibria for complex solids and solutions, and in particular for biominerals. It has been shown that the conventional method of equilibration over a large excess of solid is inappropriate for the investigation of solubility when there is incongruent dissolution.
Chen, ZF, Darvell, BW, Pan, HB
openaire +4 more sources
A method for estimating both the solubility parameters and molar volumes of liquids
, 1974The solubility parameters and molar volumes of substances can be used, in conjunction with suitable theory, to provide estimates of the thermodynamic properties of solutions; the solubility characteristics of polymer-solvent systems and the estimation of
R. Fedors
semanticscholar +1 more source
On Solubility and Solubility Product Constants
Soil Science Society of America Journal, 1973K. L. Babcock, G. M. Marion
openaire +4 more sources
Current Opinion in Biotechnology, 1993
The solubility and secretability of proteins can often be affected by extremely small changes in their primary structure. Attempts to determine empirical rules for the alteration of protein structure to improve either of these characteristics have met with only partial success.
openaire +3 more sources
The solubility and secretability of proteins can often be affected by extremely small changes in their primary structure. Attempts to determine empirical rules for the alteration of protein structure to improve either of these characteristics have met with only partial success.
openaire +3 more sources