Modification of Soluble Immunological Parameters during Treatment with Interleukin-2
In the present study we tested numerous soluble immunological parameters (soluble Interleukin 2 receptor, Beta 2 microglobulin, Neopterin, soluble CD8 antigen, gamma Interferon and alpha Tumor Necrosis Factor) in sera obtained from 18 advanced cancer ...
I. Abbate +6 more
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Repurposing Interleukin-6 Inhibitors to Combat COVID-19. [PDF]
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which is associated
Kato, Shumei, Kurzrock, Razelle
core +1 more source
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
core +1 more source
Cytokine soluble receptors in perinatal and early neonatal life
Background: In contrast to cellular receptors, soluble receptors do not enhance the cellular activation because they do not have transmembranic and cytoplasmic parts, acting thereby as endogenous regulatory mechanisms against systemic functions of ...
Efthimia Protonotariou +5 more
doaj +1 more source
BODY IRON STATUS INDICATORS AND INFLAMMATION INDICATORS DURING INFLAMMATORY BOWEL DISEASE THERAPY IN CHILDREN AND ADOLESCENTES [PDF]
BACKGROUND: The treatment of patients with inflammatory bowel disease (IBD) consists of the induction and maintenance remission of the disease. Iron status indicators would be useful for the diagnosis of iron deficiency anemia, whereas the inflammation ...
Fernanda F CORRÊA, Vera L SDEPANIAN
doaj +1 more source
New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity. [PDF]
Interleukin-15 (IL-15) is a potent cytokine that increases CD8+ T and NK cell numbers and function in experimental models. However, obstacles remain in using IL-15 therapeutically, specifically its low potency and short in vivo half-life.
Alpdogan, Onder +8 more
core +3 more sources
Soluble interleukin‐2 receptors in systemic lupus erythematosus [PDF]
AbstractWe studied levels of soluble interleukin‐2 receptors (IL‐2R), which are released by activated lymphocytes, in 139 serum samples from 12 patients with systemic lupus erythematosus (SLE). Concentrations of soluble IL‐2R were significantly increased in SLE patients compared with controls (P < 0.001), and they were significantly higher in ...
R E, Wolf, W G, Brelsford
openaire +2 more sources
Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C +27 more
core +1 more source
Profile of reslizumab in eosinophilic disease and its potential in the treatment of poorly controlled eosinophilic asthma [PDF]
Peer reviewedPublisher ...
Walsh, Garry Michael
core +2 more sources
Soluble interleukin‐2 receptors in children with kawasaki syndrome [PDF]
AbstractWe studied levels of soluble interleukin‐2 receptors (IL‐2R) in serial serum samples obtained from 93 patients with Kawasaki syndrome, using a double‐antibody “sandwich” enzyme‐linked immunosorbent assay technique. Concentrations of soluble IL‐2R were significantly increased in Kawasaki syndrome patients in the first 4 weeks of illness when ...
K S, Barron +6 more
openaire +2 more sources

