Results 51 to 60 of about 2,765 (249)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
General k-Dimensional Solvable Systems of Difference Equations [PDF]
Symmetry, 2017 The solvability of a k-dimensional system of difference equations of interest, which extends several recently studied ones, is investigated. A general sufficient condition for the solvability of the system is given, considerably extending some recent results in the literature.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On a solvable difference equations system
FilomatIn this paper, we study three dimensional system of difference equations. Firstly, we examine the solutions of the mentioned system depending on whether the parameters are equal to zero or non-zero. In addition, the solutions of this system are obtained in closed form.
Ömer Aktaş, Merve Kara, Yasin Yazlik
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
On an extension of a recurrent relation from combinatorics
Electronic Journal of Qualitative Theory of Differential Equations, 2017 The following recurrent relation/partial difference equation $$w_{n,k}=aw_{n-1,k-1}+bw_{n-1,k},$$ where $k,n,a,b\in\mathbb{N}$, appears in a problem in combinatorics. Here we show that an extension of the recurrent relation is solvable on, the, so called,
Stevo Stevic
doaj +1 more source
ON SOLVABILITY OF ONE DIFFERENCE EQUATION
Issues of Analysis, 2017 We consider a system of difference equation similar to those that appear as description of cumulative sums. Using Hamel bases, we construct pathological solutions to this system for constant right-hand sides. Also we show that bounded so- lutions do not exist for non-zero right-hand sides, while only constants can be solutions in the homogeneous case.
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source