Results 91 to 100 of about 7,164 (304)
Orbit decidability and the conjugacy problem for some extensions of groups
Given a short exact sequence of groups with certain conditions, 1 ? F ? G ? H ? 1, weprove that G has solvable conjugacy problem if and only if the corresponding action subgroupA 6 Aut(F) is orbit decidable.
Ventura, Enric +2 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Representations of Solvable Lie Groups
International audienceThe theory of unitary group representations began with finite groups, and blossomed in the twentieth century both as a natural abstraction of classical harmonic analysis, and as a tool for understanding various physical phenomena ...
Arnal, Didier, Currey, Bradley
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Algorithmic theory of solvable groups
The purpose of this survey is to give some picture of what is known about algorithmic and decision problems in the theory of solvable groups. We will provide a number of references to various results, which are presented without proof.
Romankov, V. A.
core +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
On Solvable Groups of Arbitrary Derived Length and Small Commutator Length
Wreath product constructions has been used to obtain for any positive integer n, solvable groups of derived length n, and commutator length at most equal to 2.
Mehri Akhavan-Malayeri
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source

