Results 41 to 50 of about 852 (252)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Matrix Representation for Decomposable Solvable Six-Dimensional Lie Algebra
مجلة التربية والعلمThis paper extends the classification of three-dimensional connected topological proper loops , for which the multiplication group is a six-dimensional decomposable solvable Lie group.
Ameer Al-Abayechi
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Advances in Mathematical Physics, 2016 It is proved that the modified Boussinesq equation is consistent Riccati expansion (CRE) solvable; two types of special soliton-cnoidal wave interaction solution of the equation are explicitly given, which is difficult to be found by other traditional ...
Wenguang Cheng, Biao Li
doaj +1 more source
On Gel′fand pairs associated with solvable Lie groups [PDF]
Transactions of the American Mathematical Society, 1990 Let G G be a locally compact group, and let
Chal Benson, Joe Jenkins, Gail Ratcliff
openaire +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Cauchy Problem for Darboux Integrable Systems and Non-Linear d'Alembert Formulas
Symmetry, Integrability and Geometry: Methods and Applications, 2013 To every Darboux integrable system there is an associated Lie group G which is a fundamental invariant of the system and which we call the Vessiot group.
Mark E. Fels, Ian M. Anderson
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Local derivation on the Schro¨dinger Lie algebra in (n+1)-dimensional space-time
Қарағанды университетінің хабаршысы. Математика сериясыThis paper investigates local derivations on the Schro¨dinger Lie algebra sn, the Lie algebra of the (n+1)dimensional space-time Schro¨dinger group. As a finite-dimensional Lie algebra that is neither semisimple nor solvable, the Schr¨odinger algebra ...
A.K. Alauadinov, B.B. Yusupov
doaj +1 more source