Results 101 to 110 of about 109,502 (302)

Methodological problems in solvency assessment of an insurance company [PDF]

open access: yes
The recent wide development and changes in insurance markets highlighted the necessity to map out the solvency analysis in a more complete framework.
Cocozza, R, Di Lorenzo, E, Sibillo, M
core   +1 more source

Social Security Reform: Possible Effects on the Elderly Poor and Mitigation Options [PDF]

open access: yes, 2008
[Excerpt] Social Security has significantly reduced elderly poverty. The elderly poverty rate has fallen from 35% in 1959 to an all-time low of 9% in 2006, in large part because of Social Security.
Romig, Kathleen
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

SOLVENCY II

open access: yesIustinianus Primus Law Review, 2014
The main purpose of this paper is to analyze Solvency II which is a new supranational insurance regulatory regime introduced by the institutions of the European Union in order to enhance the financial stability of the insurance and reinsurance ...
Biljana Petrevska
doaj  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

MODERNIZATION SCORING MODELS ASSESS THE CREDITWORTHINESS OF PJSC «SBERBANK OF RUSSIA» IN THE REGIONAL ASPECT

open access: yesВестник Северо-Кавказского федерального университета, 2022
The actual problems of assessing the creditworthiness of borrowers, the necessity of impeding the development of the informal sector, formulated measures to reduce credit risks taking into account regional factors: the expediency of introduction of a new
Oliga Pakova, Dmitry Shkolin
doaj  

Analysis of Georgia's Unemployment Insurance Trust Fund Reserves [PDF]

open access: yes, 2006
This report analyses several aspects of Georgia's Unemployment Insurance Trust Fund, including the structure and the appropriate target level for the Trust Fund balance for the state of Georgia.
Edward Sennoga
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

ACCOUNT INSTRUMENT CAPITAL BORROWED [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2012
Setting up business capital is made from different sources and their use coordinates its policy aims, issues that affect the overall efficiency and thus differentiate companies with the same profile of activity and a similar level of capital advanced in ...
Holt Gheorghe, Caruntu Genu Alexandru
doaj  

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