α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Influence of solvent on antimicrobial activity of Carlinae radix essential oil and decoct
Plants of the family Asteraceae are known for their use in ethnopharmacology, available as commercial drugs. In this study, antimicrobial activity of Carlinae radix commercial drug’s vinegar decoction and essential oil, dissolved in various solvents ...
Jović, J.+3 more
doaj
Comparative study on the gas to solution phase solvation free energies of model combustion flue gas compounds (N~2~, O~2~, CO~2~, H~2~O, SO~2~, and CO) in 178 organic solvents using the IEFPCM-UFF, CPCM, and SMD implicit solvent models at the Gaussian-4 (G4) level of theory [PDF]
Gas to solution phase Gibbs free energies of solvation at 298.15 K for transfer of six representative combustion flue gas compounds (N~2~, O~2~, CO~2~, H~2~O, SO~2~, and CO) were calculated at the Gaussian-4 (G4) level of theory using the IEFPCM-UFF ...
Kaya Forest, Sierra Rayne
core +2 more sources
Inducing Stratification of Colloidal Mixtures with a Mixed Binary Solvent [PDF]
Molecular dynamics simulations are used to demonstrate that a binary solvent can be used to stratify colloidal mixtures when the suspension is rapidly dried. The solvent consists of two components, one more volatile than the other. When evaporated at high rates, the more volatile component becomes depleted near the evaporation front and develops a ...
arxiv
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Polyelectrolyte chains in poor solvent. A variational description of necklace formation
We study the properties of polyelectrolyte chains under different solvent conditions, using a variational technique. The free energy and the conformational properties of a polyelectrolyte chain are studied minimizing the free energy $F_N$, depending on ...
Lee, Namkyung+3 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Solvent Additives: Key Morphology‐Directing Agents for Solution‐Processed Organic Solar Cells
Organic photovoltaics (OPV) have the advantage of possible fabrication by energy‐efficient and cost‐effective deposition methods, such as solution processing.
Caitlin McDowell+3 more
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source