Results 111 to 120 of about 1,927,401 (335)

Are hydrodynamic interactions important in the kinetics of hydrophobic collapse?

open access: yes, 2012
We study the kinetics of assembly of two plates of varying hydrophobicity, including cases where drying occurs and water strongly solvates the plate surfaces.
Berne, B. J.   +2 more
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

The mist-lining technique: a look into the mechanical performance and the adhesive bond strength of selected lining materials

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2017
Linings pursue the reinforcement of a weak canvas painting, generally by the adhesion of a new fabric. As referred in the specialised literature, among the technical requirements of such a treatment the new structure must present high stiffness and ...
L. Bertomeu Contreras   +2 more
doaj   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yes
FEBS Letters, EarlyView.
Igor Zivkovic   +2 more
wiley   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Influence pressure and size particle to extraction by CO2

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2008
Supercritical fluid extraction (SFE) is an efficient extraction technique for the separation of various organic compounds from herbs, or more generally, from plant materials.
Vladan MICIC   +4 more
doaj  

The Dissociative Power of Solvents [PDF]

open access: green, 1899
Louis Kahlenberg, Abraham Lincoln
openalex   +1 more source

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